Analysis of ancestry informative markers in three main ethnic groups from Ecuador supports a trihybrid origin of Ecuadorians.
Highlights
- A total of 162 Ecuadorians (Kichwa, Mestizo, and Afro-Ecuadorian) were investigated with the Precision ID Ancestry Panel.
- The genetic markers analysed showed higher levels of diversity in Afro-Ecuadorian and Mestizo compared to the Kichwa group.
- The Kichwa had the highest Native Amerindian (NAM) component of three the ethnic groups studied (91.5% in average).
- The Mestizo presented an admixed ancestry of NAM and European components, with the latter representing around 30% in average.
- Afro-Ecuadorian were highly admixed presenting proportions of African, NAM, and European ancestries.
Cancer patterns and trends in Central and South America
Highlights
- The leading incident cancers were prostate, lung, breast, cervix, colorectal, and stomach.
- These cancers were also the primary causes of cancer mortality.
- High/very high HDI countries experienced a high burden of prostate and breast cancer.
- Medium HDI countries had a high burden of stomach and cervical cancers.
- Resource-dependent interventions to prevent, diagnose, and treat cancer are urgently needed.
- Chronic gastritis with intestinal metaplasia: clinico-statistical, histological and immunohistochemical study Chronic gastritis has a high incidence in adults, causing progressive destruction of glandular structures, favoring the development of gastric atrophy. The association of chronic gastritis with intestinal type metaplasia of gastric mucosa has a poor outcome as intestinal metaplasia is regarded as a precancerous lesion. Metaplasia is common in patients with Helicobacter pylori infection and also heavy smokers. The aim of this study was to evaluate the relationship between chronic gastritis and intestinal metaplasia.
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